Joaquim Trias Selected Research

varespladib methyl

10/2010	Varespladib methyl in cardiovascular disease.
4/2009	The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
2/2009	A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.
1/2009	Varespladib (A-002), a secretory phospholipase A2 inhibitor, reduces atherosclerosis and aneurysm formation in ApoE-/- mice.

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Joaquim Trias Research Topics

Disease

4	Atherosclerosis 10/2010 - 01/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2010 - 02/2009
2	Inflammation (Inflammations) 01/2013 - 04/2009
2	Surfactant Dysfunction 01/2013 - 05/2012
2	Infections 05/2012 - 10/2003
1	Acute Lung Injury 01/2013
1	Necrosis 01/2013
1	Hyaline Membrane Disease 05/2012
1	Pneumonia (Pneumonitis) 05/2012
1	Meconium Aspiration Syndrome 05/2012
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 05/2012
1	Lung Injury 05/2012
1	Coronary Disease (Coronary Heart Disease) 10/2010
1	Acute Coronary Syndrome 10/2010
1	Aneurysm (Aneurysms) 01/2009
1	Respiratory Tract Infections (Respiratory Tract Infection) 12/2003

Drug/Important Bio-Agent (IBA)

6	Secretory Phospholipases A2IBA 01/2013 - 01/2009
5	varespladibIBA 01/2013 - 01/2009
4	varespladib methylIBA 10/2010 - 01/2009
3	EnzymesIBA 05/2012 - 01/2009
2	Surface-Active Agents (Surfactants)IBA 01/2013 - 05/2012
2	Proteins (Proteins, Gene)FDA Link 01/2013 - 05/2012
2	Apolipoproteins E (ApoE)IBA 04/2009 - 01/2009
1	Nonesterified Fatty Acids (NEFA)IBA 01/2013
1	Lipoproteins (Lipoprotein)IBA 10/2010
1	Phospholipases (Phospholipase)IBA 10/2010
1	IsoenzymesIBA 10/2010
1	Biomarkers (Surrogate Marker)IBA 10/2010
1	Aryldialkylphosphatase (Paraoxonase)IBA 04/2009
1	Pravastatin (Pravachol)FDA LinkGeneric 04/2009
1	LipidsIBA 04/2009
1	PLIalphaIBA 02/2009
1	Angiotensin IIIBA 01/2009
1	CholesterolIBA 01/2009
1	Oxazolidinones (2 Oxazolidone)IBA 12/2003
1	Vancomycin FDA LinkGeneric 10/2003

Therapy/Procedure

1	Therapeutics 10/2010